Halogenated Nucleosides
2',3'-Dideoxy-3'-fluoro-5-methylcytidine
Quick view. 2',3'-Dideoxy-3'-fluoro-5-methylcytidine is a fluorinated cytidine nucleoside with CAS 115249-95-1. CAS 115249-95-1. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2',3'-Dideoxy-3'-fluoro-5-methylcytidine is classified as fluorinated cytidine nucleoside (Formula C10H14FN3O3; molecular weight 243.23).
2',3'-Dideoxy-3'-fluoro-5-methylcytidine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For 2',3'-Dideoxy-3'-fluoro-5-methylcytidine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- Cytidine, 2',3'-dideoxy-3'-fluoro-5-methyl-
- Wikidata Q90559154
Useful catalog search terms
- CAS 115249-95-1
- YTMNCNXZZRCBFC-XLPZGREQSA-N
- PubChem CID 451565
Physicochemical data
| SMILES | CC1=CN(C(=O)N=C1N)[C@H]2C[C@@H]([C@H](O2)CO)F |
|---|---|
| Structural feature | 2',3'-dideoxy sugar bearing 3'-fluoro substitution |
| PubChem CID | 451565 |
| InChIKey | YTMNCNXZZRCBFC-XLPZGREQSA-N |
| InChI | InChI=1S/C10H14FN3O3/c1-5-3-14(10(16)13-9(5)12)8-2-6(11)7(4-15)17-8/h3,6-8,15H,2,4H2,1H3,(H2,12,13,16)/t6-,7+,8+/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2',3'-Dideoxy-3'-fluoro-5-methylcytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Dideoxy-3'-fluoro-5-methylcytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0157 and CAS 115249-95-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.