Modified Nucleosides
2',3'-Dideoxycytidine
Quick view. We supply 2',3'-Dideoxycytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 7481-89-2. Catalog target purity: Specification on request.
Product profile
2',3'-Dideoxycytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H13N3O3; molecular weight 211.22).
2',3'-Dideoxycytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-Dideoxycytidine, reported solubility: DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Sonicated). Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- zalcitabine
- DC
- D 2C
- Hivid
- ddCyd
- I-livid
- 2',3'-ddC
- NSC 606170
Useful catalog search terms
- CAS 7481-89-2
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | 1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s |
|---|---|
| InChIKey | WREGKURFCTUGRC-POYBYMJQSA-N |
| SMILES | NC1=NC(=O)N(C=C1)[C@H]2CC[C@@H](CO)O2 |
| Melting point | 217-218 °C(lit.) |
| Boiling point | 350.9°C (rough estimate) |
| Density | 1.2605 (rough estimate) |
| pKa | 14.44±0.10(Predicted) |
| Form | powder |
| Color | colorless |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxycytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2',3'-Dideoxycytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0667 and CAS 7481-89-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.