Ac-protected Nucleosides
2', 3'-O-Ac-rG(iBu)
Quick view. We supply 2', 3'-O-Ac-rG(iBu) as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 163586-86-5. Catalog target purity: Specification on request.
Product profile
2', 3'-O-Ac-rG(iBu) is classified as nucleoside or protected nucleoside intermediate (Formula C18H23N5O8; molecular weight 437.41).
2', 3'-O-Ac-rG(iBu) — N-Isobutyryl-2',3'-Acetyl-Guanosine is a guanosine nucleoside derivative.
For 2', 3'-O-Ac-rG(iBu), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N-Isobutyryl-2', 3'-Acetyl-Guanosine
- Guanosine-9-17N, N-(2-methyl-1-oxopropyl)-, 2',3'-diacetate
Useful catalog search terms
- CAS 163586-86-5
- Nucleoside or protected nucleoside intermediate
- Ac-protected Nucleosides
Physicochemical data
| Density | 1.62±0.1 g/cm3(Predicted) |
|---|---|
| pKa | 8.68±0.20(Predicted) |
| SMILES | O([C@@H]1[C@@H]([C@@H](CO)O[C@H]1N1C=NC2C(N=C(NC(=O)C(C)C)NC1=2)=O)OC(=O)C)C(=O)C |&1:1,2,3,7,r| |
| InChIKey | HWVKXBNLKJAPSV-ITXRQAIFNA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2', 3'-O-Ac-rG(iBu) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Frequently asked questions
Can the package size for 2', 3'-O-Ac-rG(iBu) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0094 and CAS 163586-86-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Ac-protected Nucleosides product family and its named chemistry.