Base-protected Nucleosides
2'-dG(iBu)
Quick view. We supply 2'-dG(iBu) as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 68892-42-2. Catalog target purity: Specification on request.
Product profile
2'-dG(iBu) is classified as nucleoside or protected nucleoside intermediate (Formula C14H19N5O5; molecular weight 337.33).
2'-dG(iBu) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-dG(iBu), storage: −20°C. Form: powder to crystal.
Names and search terms
Confirmed or normalized name variants
- DG-IBU
- N2-(2-METHYLPROPANOYL)-2'DEOXY-GUANOSINE
- N2-ISOBUTYROYL-2'-DEOXYGUANOSINE
- N2-ISOBUTYRYL-2'-DEOXYGUANOSINE
- N2-ISOBUTYRYLDEOXYGUANOSINE
- N-IB-DG
- 2’-deoxy-n-(2-methyl-1-oxopropyl)-guanosin
- ibu-deoxyguanosine
Useful catalog search terms
- CAS 68892-42-2
- Nucleoside or protected nucleoside intermediate
- Base-protected Nucleosides
Physicochemical data
| Melting point | ≥300 °C |
|---|---|
| Density | 1.72±0.1 g/cm3(Predicted) |
| pKa | 9.16±0.20(Predicted) |
| Form | powder to crystal |
| Color | White to Almost white |
| SMILES | OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)C[C@@H]1O |
| InChI | InChI=1S/C14H19N5O5/c1-6(2)12(22)17-14-16-11-10(13(23)18-14)15-5-19(11)9-3-7(21)8(4-20)24-9/h5-9,20-21H,3-4H2,1-2H3,(H2,16,17,18,22,23)/t7-,8+,9+/m0/s |
| InChIKey | SIDXEQFMTMICKG-DJLDLDEBSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2'-dG(iBu) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0109 and CAS 68892-42-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Base-protected Nucleosides product family and its named chemistry.