2'-F-ANA Phosphoramidites
2'-F-ANA-dU Phosphoramidite
Quick view. We supply 2'-F-ANA-dU Phosphoramidite as a 2'-F-ANA phosphoramidite for synthesizing fluoro-arabino modified oligonucleotides. CAS 1190089-70-3. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2'-F-ANA-dU Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C39H46FN4O8P; molecular weight 748.79).
2'-F-ANA-dU Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For 2'-F-ANA-dU Phosphoramidite, reported solubility: DMSO: Sparingly soluble: 1-10 mg/ml Ethanol: Sparingly soluble: 1-10 mg/ml.
Names and search terms
Confirmed or normalized name variants
- 2'-F-2'-ara-dU Phosphoramidite
- 2'-F-dU-ANA-CE Phosphoramidite
- 2'-ara-2'-F-2'-dU Phosphoramidite
- 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite
- 5'-O-DMT-2'-F-2'-arabinofuranosyl-deoxyuridine 3'-CE phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro--D-arabinouridine-3'-CED-phosphoramidite
- 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro--D-arabinouridine-3'-CEN-phosphoramidite
- 5’-O-(4,4’-Dimethoxytrityl)-2’-deoxy-2’-fluoro-b-D-arabinouridine-3’-CED-phosphoramidite
Useful catalog search terms
- CAS 1190089-70-3
- Protected oligonucleotide phosphoramidite building block
- 2'-fluoro modification
- phosphoramidite coupling group
- 2'-F-ANA Phosphoramidites
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-F-ANA-dU Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2FAP-00022'-F-ANA-dC(Ac) Phosphoramidite
2'-F-ANA Phosphoramidites · CAS: N/A
BX-2FAP-00032'-F-ANA-dG(ibu) Phosphoramidite
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BX-2FAP-00052'-F-ANA-dC(Bz) Phosphoramidite
2'-F-ANA Phosphoramidites · CAS: 1404463-12-2
BX-2FAP-00145'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite
2'-F-ANA Phosphoramidites · CAS: N/A
BX-2FAP-00105'-Dimethoxytrityl-N2-isobutyryl-2'-deoxy-2'-fluoroarabinoguanosine 3'-[(2-cyanoethyl)-(N, N-diisopropyl)]-phosphoramidite
2'-F-ANA Phosphoramidites · CAS: N/A
Frequently asked questions
Can the package size for 2'-F-ANA-dU Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FAP-0004 and CAS 1190089-70-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2'-F-ANA-dU Phosphoramidite or the named structural feature represented by this product.