Ara Nucleosides
2-fluoro-arabinoadenosine
Quick view. We supply 2-fluoro-arabinoadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 21679-14-1. Catalog target purity: Specification on request.
Product profile
2-fluoro-arabinoadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12FN5O4; molecular weight 285.23).
2-fluoro-arabinoadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-fluoro-arabinoadenosine, reported solubility: DMF: 20 mg/mL, clear, faintly yellow. Storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- fludarabine
- 2-F-ARAA
- 2-FLUORO-9-ARABINOADENINE
- 2-fluoroadenine-9-bata-d-arabinofuranoside
- 2-FLUOROADENINE 9-BETA-D-ARABINOFURANOSIDE
- 6-AMINO-9 BETA-D-ARABINOFURANOSYLFLUOROPURINE
- 9-bata-d-arabinofuranosyl-2-fluoroadenine
- 9-BETA-D-ARABINOFURANOSYL-2-FLUORO-9H-PURIN-6-AMINE
Useful catalog search terms
- CAS 21679-14-1
- Nucleoside or protected nucleoside intermediate
- Ara Nucleosides
Physicochemical data
| InChI | InChI=1/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/s |
|---|---|
| InChIKey | HBUBKKRHXORPQB-VOSPVXAENA-N |
| SMILES | C12N=C(N=C(N)C=1N=CN2[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1)F |&1:10,11,13,15,r| |
| Melting point | 265-268°C |
| Boiling point | 747.3±70.0 °C(Predicted) |
| Density | 2.17±0.1 g/cm3(Predicted) |
| pKa | 13.05±0.70(Predicted) |
| Form | Powder |
| Color | White to Pale Yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2-fluoro-arabinoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-fluoro-arabinoadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-ARN-0028 and CAS 21679-14-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2-fluoro-arabinoadenosine or the named structural feature represented by this product.