Modified Nucleosides
2-Methylthioadenosine
Quick view. We supply 2-Methylthioadenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 4105-39-9. Catalog target purity: Specification on request.
Product profile
2-Methylthioadenosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O4S; molecular weight 313.33).
2-Methylthioadenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-Methylthioadenosine, form: Solid.
Names and search terms
Confirmed or normalized name variants
- 2-(Methylsulfanyl)-9-pentofuranosyl-9H-purin-6-amine
- Zeatin Impurity
- Adenosine, 2-(methylthio)-
- 2-Methylthioadenosine ( 2-MeS-Ado )
- 2-[6-AMINO-2-(METHYLSULFANYL)PURIN-9-YL]-5-(HYDROXYMETHYL)OXOLANE-3,4-DIOL
- 2-Methylthioadenosine ADA inhibitor,platelet ADP receptor (made from GL101374)
Useful catalog search terms
- CAS 4105-39-9
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C11H15N5O4S/c1-21-11-14-8(12)5-9(15-11)16(3-13-5)10-7(19)6(18)4(2-17)20-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7-,10-/m1/s |
|---|---|
| InChIKey | AJNDEAZTAFKOOO-KQYNXXCUSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=C(SC)N=3)N)N=C2)[C@H](O)[C@@H]1O |
| Melting point | 225 °C |
| Boiling point | 747.6±70.0 °C(Predicted) |
| Density | 1.98±0.1 g/cm3(Predicted) |
| pKa | 13.08±0.70(Predicted) |
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 2-Methylthioadenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0529 and CAS 4105-39-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.