Modified Nucleotides
2-Thio-UTP Sodium Salt
Quick view. We supply 2-Thio-UTP Sodium Salt as a sulfur-modified nucleotide analog for phosphorothioate, enzyme-mechanism and nuclease-resistance research. CAS 35763-29-2. Catalog target purity: Specification on request.
Product profile
2-Thio-UTP Sodium Salt is classified as nucleotide or nucleotide analog (Formula C9H15N2O14P3S; molecular weight 500.21).
2-Thio-UTP Sodium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For 2-Thio-UTP Sodium Salt, storage: Store at -20°C.
Names and search terms
Confirmed or normalized name variants
- 2-ThioUTP tetrasodium salt
- 2-Thiouridine5'-triphosphatetetrasodiumsalt
- Uridine 5'-(tetrahydrogen triphosphate), 2-thio-
- 2 ThioUTP tetrasodium salt,2ThioUTP tetrasodium salt
- Disodium 1-(5-O-{[(hydroxyphosphinato)oxy]phosphinato}-beta-D-ribofuranosyl)-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one
Useful catalog search terms
- CAS 35763-29-2
- Nucleotide or nucleotide analog
- triphosphate group
- Modified Nucleotides
Physicochemical data
| Key chemistry motifs | triphosphate group |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
| Density | 2.09±0.1 g/cm3(Predicted) |
| pKa | 0.97±0.50(Predicted) |
| InChI | InChI=1S/C9H14N2O11P2S.2Na/c12-5-1-2-11(9(25)10-5)8-7(14)6(13)4(21-8)3-20-24(18,19)22-23(15,16)17;;/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,10,12,25)(H2,15,16,17);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m../s |
| InChIKey | XZPMKLNUNBQGSH-WFIJOQBCSA-L |
| SMILES | O=P([O-])(O)OP(=O)(O)OC[C@H]1O[C@@H](n2ccc([O-])nc2=S)[C@H](O)[C@@H]1O.[Na+].[Na+] |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
These points describe 2-Thio-UTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-OMe-GDP Disodium Salt
Modified Nucleotides · CAS: 78771-34-3
BX-INTE-00143'-OMe-GMP
Modified Nucleotides · CAS: 400806-41-9
BX-INTE-00153'-OMe-GMP TEA Salt
Modified Nucleotides · CAS: 860605-85-2
BX-INTE-0021Im-3'-OMe-GMP
Modified Nucleotides · CAS: 1005791-93-4
BX-INTE-0023Im-GDP
Modified Nucleotides · CAS: 1199264-75-9
BX-MN-0025(-)-Emtricitabine Triphosphate Tetrasodium Salt
Modified Nucleotides · CAS: 1188407-46-6
Frequently asked questions
Can the package size for 2-Thio-UTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0039 and CAS 35763-29-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 2-Thio-UTP Sodium Salt or the named structural feature represented by this product.