Halogenated Nucleosides
3'-Deoxy-3'-fluoro-xylo-cytidine
Quick view. Xylo-cytidine derivative bearing fluorine at C3' and no 3'-hydroxyl group. CAS 26563-01-9. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
3'-Deoxy-3'-fluoro-xylo-cytidine is classified as halogenated nucleosides (Formula C9H12FN3O4; molecular weight 245.21 g/mol).
3'-Deoxy-3'-fluoro-xylo-cytidine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 3'-Deoxy-3'-fluoro-xylo-cytidine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 3'-Deoxy-3'-fluoroxylocytidine
- 26563-01-9
Physicochemical data
| PubChem CID | 59795629 |
|---|---|
| Systematic name | 4-amino-1-[(2R,3S,4R,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| Chemical form | Neutral 3'-deoxy-3'-fluoro-xylo-cytidine stereoisomer |
| Structural scope | Fluorine at C3' in place of the 3'-hydroxyl group |
| Stereochemical scope | Four defined sugar-ring stereocenters |
| InChIKey | PKOBNLOZXOHYOP-PXBUCIJWSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 3'-Deoxy-3'-fluoro-xylo-cytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-Deoxy-3'-fluoro-xylo-cytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0205 and CAS 26563-01-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.