Amino-modified Nucleosides
3'-NH₂-ddG
Quick view. We supply 3'-NH₂-ddG as a guanosine 3'-amino dideoxy analog for modified nucleotide synthesis and enzyme studies. CAS 66323-49-7. Catalog target purity: ≥99%.
Product profile
3'-NH₂-ddG is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N6O3; molecular weight 266.26).
3'-NH₂-ddG can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-NH₂-ddG, storage: under inert gas (nitrogen or Argon) at 2–8 °C. Form: Powder.
Names and search terms
Confirmed or normalized name variants
- -Amino-2&rsquo
- 3'-AMINO-2'-DEOXY-D- GUANOSINE
- 3'-AMINO-2',3'-DIDEOXYGUANOSINE
- Guanosine,3'-aMino-2',3'-dideoxy-
- 3'-Amino-2',3'-dideoxy-D-guanosine
- 9-(3-Amino-2,3-dideoxy-β-D-ribofuranosyl)guanine
- 2-amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6 -one
- 2-Amino-9-[(2R,4S,5S)-4-amino-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one USP/EP/BP
Useful catalog search terms
- CAS 66323-49-7
- Nucleoside or protected nucleoside intermediate
- Amino-modified Nucleosides
Physicochemical data
| Form | Powder |
|---|---|
| Color | Off-white to Yellow |
| InChI | InChI=1S/C10H14N6O3/c11-4-1-6(19-5(4)2-17)16-3-13-7-8(16)14-10(12)15-9(7)18/h3-6,17H,1-2,11H2,(H3,12,14,15,18)/t4-,5+,6+/m0/s |
| InChIKey | HOQBPAWPBCAUGA-KVQBGUIXSA-N |
| SMILES | N=c1nc(O)c2ncn([C@H]3C[C@H](N)[C@@H](CO)O3)c2[nH]1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 3'-NH₂-ddG or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3'-NH₂-ddG be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0008 and CAS 66323-49-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.