Modified Nucleosides
4-Thiouridine
Quick view. A beta-D-ribonucleoside in which the carbonyl oxygen at uracil C4 is replaced by sulfur, CAS 13957-31-8. CAS 13957-31-8. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
4-Thiouridine is classified as modified nucleosides (Formula C9H12N2O5S; molecular weight 260.27).
Reported in Nature Protocols 2020 for TTchem-seq workflows that label and capture newly synthesized RNA using 4-thiouridine.
For 4-Thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 4sU
- 4-Thio-D-uridine
- Uridine, 4-thio-
Useful catalog search terms
- CAS 13957-31-8
- PubChem CID 3032615
- Wikidata Q20890501
Physicochemical data
| IUPAC name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one |
|---|---|
| InChI | InChI=1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1 |
| InChIKey | ZLOIGESWDJYCTF-XVFCMESISA-N |
| SMILES | C1=CN(C(=O)NC1=S)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O |
| Nucleobase modification | Uracil C4 thione |
| Sugar | beta-D-Ribofuranose |
| Hydroxyl state | Free 2', 3' and 5' hydroxyls |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
(S)-cEt-rA
Modified Nucleosides · CAS: 1197033-34-3
BX-OP-0069S-Adenosyl-L-methionine (SAM)
Modified Nucleosides · CAS: 485-80-3
BX-MN-01875-(Carboxyhydroxymethyl)uridine
Modified Nucleosides · CAS: 934743-11-0
BX-MN-0719(R)-N6-(2,3-Dihydro-1H-inden-1-yl)adenosine
Modified Nucleosides · CAS: 96392-15-3
BX-MN-01972,2'-Cyclocytidine hydrochloride
Modified Nucleosides · CAS: 10212-25-6
BX-MN-0199N3-Allyluridine
Modified Nucleosides · CAS: 103951-13-9
Frequently asked questions
Can the package size for 4-Thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0521 and CAS 13957-31-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.