Intermediates
5-(2-Hydroxyethyl)-2-thiouracil
Quick view. We supply 5-(2-Hydroxyethyl)-2-thiouracil as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 23956-11-8. Catalog target purity: Specification on request.
Product profile
5-(2-Hydroxyethyl)-2-thiouracil is classified as specialty research-use chemical building block (Formula C6H8N2O2S; molecular weight 172.2).
5-(2-Hydroxyethyl)-2-thiouracil can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
For 5-(2-Hydroxyethyl)-2-thiouracil, dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
Names and search terms
Confirmed or normalized name variants
- NSC 528411
- 2,3-Dihydro-5-(2-hydroxyethyl)-2-thioxo-4(1H)-pyriMidinone
- 5-(2-Hydroxyethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
- 4(1H)-Pyrimidinone, 2,3-dihydro-5-(2-hydroxyethyl)-2-thioxo-
- 5-(2-hydroxyethyl)-2-sulfanylidene-1,2,3,4-tetrahy
- dropyrimidin-4-one
Useful catalog search terms
- CAS 23956-11-8
- Specialty research-use chemical building block
- fluorescent label
- Intermediates
Physicochemical data
| Key chemistry motifs | fluorescent label |
|---|---|
| InChI | InChI=1S/C6H8N2O2S/c9-2-1-4-3-7-6(11)8-5(4)10/h,9H,1-2H2,(H2,7,8,10,11) |
| InChIKey | BHOFBQMOMPQKCN-UHFFFAOYSA-N |
| SMILES | OCCc1cnc(S)nc1O |
| Density | 1.45±0.1 g/cm3(Predicted) |
| pKa | 7.57±0.25(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Fluorescent labels enable non-radioactive detection and can reduce downstream staining or secondary-label steps.
Method limitations
- Dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
These points describe 5-(2-Hydroxyethyl)-2-thiouracil or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-(2-Hydroxyethyl)-2-thiouracil be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-INTE-0069 and CAS 23956-11-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5-(2-Hydroxyethyl)-2-thiouracil or the named structural feature represented by this product.