Halogenated Nucleosides
5-Bromouridine
Quick view. We supply 5-Bromouridine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 957-75-5. Catalog target purity: Specification on request.
Product profile
5-Bromouridine is classified as nucleoside or protected nucleoside intermediate (Formula C9H11BrN2O6; molecular weight 323.1).
5-Bromouridine is a uridine derivative and is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry.
For 5-Bromouridine, reported solubility: Water (Sonicated). Storage: 0-6°C.
Names and search terms
Confirmed or normalized name variants
- 5-BROMOURACIL-1-BETA-D-RIBOFURANOSIDE
- 1-beta-ribofuranosyl-5-bromo-uracil
- 5-bromo-uridin
- 5-bromouracil-1-β-d-ribofuranoside
- 5-Bromo-D-uridine
- 5-BROMO-URIDINE(5-BRU)
- 5-BROMOURIDINE (5-BROMOURACIL-1-β-D-RIBOFURANOSIDE: 5-BRU)
- 5-BROMOURIDINE extrapure
Useful catalog search terms
- CAS 957-75-5
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C9H11BrN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s |
|---|---|
| InChIKey | AGFIRQJZCNVMCW-UAKXSSHOSA-N |
| SMILES | C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)Br |
| Melting point | 180-182 °C (dec.) (lit.) |
| Density | 1.9322 (rough estimate) |
| pKa | 7.73±0.10(Predicted) |
| Form | Solid |
| Color | Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5-Bromouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5-Bromouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0148 and CAS 957-75-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.