Modified Nucleosides
5-Methyl-4'-thiouridine
Quick view. We supply 5-Methyl-4'-thiouridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 6741-71-5. Catalog target purity: Specification on request.
Product profile
5-Methyl-4'-thiouridine is classified as nucleoside or protected nucleoside intermediate (Formula C10H14N2O5S; molecular weight 274.29).
5-Methyl-4'-thiouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-Methyl-4'-thiouridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 1-(4'-Thio-beta-ribofuranosyl)thymine
- Uridine, 5-methyl-4'-thio-
- Uridine,5-methyl-4'-thio- (7CI,8CI,9CI)
- 1-(4-thio-beta-D-ribofuranosyl)-5-Methyluracil
- 5-Methyl-4’-thiouridine, 1-(4-thio-beta-D-ribofuranosyl)-5-methyluracil
Useful catalog search terms
- CAS 6741-71-5
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H14N2O5S/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s |
|---|---|
| InChIKey | CKHFVQVATAWGSH-JXOAFFINSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](S2)CO)O)O |
| Density | 1.592±0.06 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
(S)-cEt-rA
Modified Nucleosides · CAS: 1197033-34-3
BX-OP-0069S-Adenosylmethionine (SAM)
Modified Nucleosides · CAS: 485-80-3
BX-MN-0185(R-/S-) 5-Carbamoylhydroxy methyluridine
Modified Nucleosides · CAS: N/A
BX-MN-0186(R-/S-)5-(1-Hydroxy)(methoxycarbonyl)methyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0187(R-/S-)5-Carboxyhydroxymethyl uridine
Modified Nucleosides · CAS: N/A
BX-MN-0719(R)-N-(2,3-dihydro-1H-indenyl)adenosine
Modified Nucleosides · CAS: 96392-15-3
Frequently asked questions
Can the package size for 5-Methyl-4'-thiouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0630 and CAS 6741-71-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.