DMTr-protected Nucleosides
5'-O-DMTr-2'-dT
Quick view. We supply 5'-O-DMTr-2'-dT as a DMTr-protected nucleoside intermediate for selective oligonucleotide building-block synthesis. CAS 40615-39-2. Catalog target purity: ≥95%.
Product profile
5'-O-DMTr-2'-dT is classified as nucleoside or protected nucleoside intermediate (Formula C31H32N2O6; molecular weight 528.6).
5'-O-DMTr-2'-dT can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-DMTr-2'-dT, reported solubility: Chloroform (Slightly), Methanol (Slightly). Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 5'-DIMETHOXYTRITYL THYMIDINE
- 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYTHYMIDINE
- 5'-O-(4,4'-DIMETHOXYTRITYL)THYMIDINE
- 5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-deoxythymidine
- 5'-O-DIMETHOXYTRITYL-DEOXYTHYMIDINE
- 5'-O-(DIMETHOXYTRITYL)-THYMIDINE
- 5'-O-DMT-THYMIDINE
- DMT-DT
Useful catalog search terms
- CAS 40615-39-2
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|---|
| Melting point | 114-116 °C (subl.)(lit.) |
| Boiling point | 618.41°C (rough estimate) |
| Density | 1.2483 (rough estimate) |
| pKa | 9.55±0.10(Predicted) |
| Form | Powder |
| Color | White to off-white |
| SMILES | COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2O)N3C=C(C)C(=O)NC3=O)(c4ccccc4)c5ccc(OC)cc5 |
| InChIKey | UBTJZUKVKGZHAD-UPRLRBBYSA-N |
| InChI | InChI=1S/C31H32N2O7/c1-20-18-33(30(36)32-29(20)35)28-17-26(34)27(40-28)19-39-31(21-7-5-4-6-8-21,22-9-13-24(37-2)14-10-22)23-11-15-25(38-3)16-12-23/h4-16,18,26-28,34H,17,19H2,1-3H3,(H,32,35,36)/t26-,27+,28+/m0/s |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-DMTr-2'-dT be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0052 and CAS 40615-39-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry.