Halogenated Nucleosides
5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine
Quick view. We supply 5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 34627-62-8. Catalog target purity: Specification on request.
Product profile
5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine is classified as nucleoside or protected nucleoside intermediate (Formula C29H27ClN2O4; molecular weight 502.989).
5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine — 3’-Chloro-3''-deoxy-5’-O-tritylthymidine (cas# 34627-62-8) is a compound useful in organic synthesis.
For 5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine, reported solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated). Storage: Refrigerator.
Names and search terms
Confirmed or normalized name variants
- 3'-Chloro-3'-deoxy-5'-O-(triphenylmethyl)thymidine
- 3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE
Useful catalog search terms
- CAS 34627-62-8
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C29H27ClN2O4/c1-20-18-32(28(34)31-27(20)33)26-17-24(30)25(36-26)19-35-29(21-11-5-2-6-12-21,22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,18,24-26H,17,19H2,1H3,(H,31,33,34)/t24-,25+,26+/m0/s |
|---|---|
| InChIKey | UPBVZHGDVFKZMX-JIMJEQGWSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)Cl |
| Melting point | 138-140°C |
| Density | 1.33±0.1 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
| Form | Solid |
| Color | Off-White to Light Yellow |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 5'-O-Triphenylmethyl-3'-deoxy-3'-chlorothymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0106 and CAS 34627-62-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.