DMTr-protected Nucleosides
6'-O-DMTr-2',3'-dideoxy-Homo-C
Quick view. We supply 6'-O-DMTr-2',3'-dideoxy-Homo-C as a protected homo-cytidine analog for non-natural nucleoside and backbone-extended oligonucleotide building-block synthesis. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%.
Product profile
6'-O-DMTr-2',3'-dideoxy-Homo-C is classified as nucleoside or protected nucleoside intermediate.
6'-O-DMTr-2',3'-dideoxy-Homo-C can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 6'-O-DMTr-2',3'-dideoxy-Homo-C, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- 6'-O-DMT-2',3'-dideoxy-Homo-C
Useful catalog search terms
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 6'-O-DMTr-2',3'-dideoxy-Homo-C or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 6'-O-DMTr-2',3'-dideoxy-Homo-C be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0059, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry.