Halogenated Nucleosides
8-Bromoguanosine
Quick view. We supply 8-Bromoguanosine as a halogenated nucleoside analog for modified nucleoside, antiviral/antimetabolite and oligonucleotide precursor research. CAS 4016-63-1. Catalog target purity: Specification on request.
Product profile
8-Bromoguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12BrN5O5; molecular weight 362.14).
8-Bromoguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Bromoguanosine, reported solubility: DMSO, Methanol (Sparingly), Hot Water. Storage: −20°C.
Names and search terms
Confirmed or normalized name variants
- 2-AMINO-8-BROMO-6-HYDROXYPURINE RIBOSIDE
- 8-Bromo-D-guanosine
Useful catalog search terms
- CAS 4016-63-1
- Nucleoside or protected nucleoside intermediate
- Halogenated Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H12BrN5O5/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8/h,4-5,8,17-19H,1H2,(H3,12,14,15,20)/t2-,4-,5-,8-/m1/s |
|---|---|
| InChIKey | ASUCSHXLTWZYBA-UMMCILCDSA-N |
| SMILES | C([C@@H]1[C@H]([C@H]([C@@H](O1)N2C3=C(C(=O)N=C(N3)N)N=C2Br)O)O)O |
| Melting point | 222°C |
| Boiling point | 774.0±70.0 °C(Predicted) |
| Density | 2.62±0.1 g/cm3(Predicted) |
| pKa | 13.00±0.70(Predicted) |
| Form | Powder |
| Color | Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Bromoguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-HN-0111 and CAS 4016-63-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry.