Modified Nucleosides
8-Methylguanosine
Quick view. We supply 8-Methylguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 36799-17-4. Catalog target purity: Specification on request.
Product profile
8-Methylguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C11H15N5O5; molecular weight 297.27).
8-Methylguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 8-Methylguanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Useful catalog search terms
- CAS 36799-17-4
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C11H15N5O5/c1-3-13-5-8(14-11(12)15-9(5)20)16(3)10-7(19)6(18)4(2-17)21-10/h4,6-7,10,17-19H,2H2,1H3,(H3,12,14,15,20)/t4-,6-,7-,10-/m1/s |
|---|---|
| InChIKey | AINAVEKHKYYDMI-KQYNXXCUSA-N |
| SMILES | Cc1nc2c(O)nc(=N)[nH]c2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
| Density | 2.11±0.1 g/cm3(Predicted) |
| pKa | 9.83±0.20(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 8-Methylguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0500 and CAS 36799-17-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.