Cyclic Dinucleotides
c-di-AMP
Quick view. Cyclic bis(3',5')-diadenylate for bacterial second-messenger and innate-immune pathway research; formula and molecular weight are stated on a free-acid basis. CAS 54447-84-6. Catalog target purity: >99% HPLC. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
c-di-AMP is classified as cyclic dinucleotides (Formula C20H24N10O12P2 (free-acid basis); molecular weight 658.41 (free-acid basis)).
c-di-AMP — Bacterial cyclic-dinucleotide and second-messenger research
For c-di-AMP, activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
Names and search terms
Confirmed or normalized name variants
- Cyclic di-AMP
- cyclic diadenosine monophosphate
- 3',5'-cyclic diadenylic acid
Useful catalog search terms
- 54447-84-6
Physicochemical data
| Linkage | Cyclic bis(3',5')-diadenylate |
|---|---|
| Parent InChIKey | PDXMFTWFFKBFIN-XPWFQUROSA-N |
| Supply Form | Commonly supplied as a sodium salt; confirm counterion stoichiometry for the requested material |
| Physical form | White to off-white solid |
| Storage temperature | -20 C |
| InChI | InChI=1S/C20H24N10O12P2/c21-15-9-17(25-3-23-15)29(5-27-9)19-11(31)13-7(39-19)1-37-43(33,34)42-14-8(2-38-44(35,36)41-13)40-20(12(14)32)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-32H,1-2H2,(H,33,34)(H,35,36)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11-,12-,13-,14-,19-,20-/m1/s1 |
| InChIKey | PDXMFTWFFKBFIN-XPWFQUROSA-N |
| SMILES | C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C(N=CN=C76)N)O)OP(=O)(O1)O)O |
| PubChem CID | 11158091 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Innate-immune pathway ligand-response studies
Product-specific evaluation notes
Potential advantages
- Defined linkage isomers and counterion forms allow controlled comparisons across cyclic-dinucleotide assay conditions.
Method limitations
- Activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
These points describe c-di-AMP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for c-di-AMP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CDN-0013 and CAS 54447-84-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.