Cyclic Dinucleotides
c-di-GMP Disodium Salt
Quick view. c-di-GMP Disodium Salt is the disodium form of cyclic diguanylate for research-use cyclic nucleotide chemistry. CAS 2222132-40-1. Catalog target purity: >99%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
c-di-GMP Disodium Salt is classified as cyclic dinucleotide (Formula C20H22N10Na2O14P2; molecular weight 734.40).
c-di-GMP Disodium Salt — Cyclic dinucleotide reagent for research workflows that specify the c-di-GMP disodium form.
For c-di-GMP Disodium Salt, activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
Names and search terms
Confirmed or normalized name variants
- Cyclic di-GMP Disodium Salt
- c-di-GMP.2Na
Useful catalog search terms
- CAS 2222132-40-1
- SVIXOIGPVFFABR-XDODWTFASA-L
- PubChem CID 137120247
Physicochemical data
| Counterion | Disodium |
|---|---|
| PubChem CID | 137120247 |
| InChIKey | SVIXOIGPVFFABR-XDODWTFASA-L |
| InChI | InChI=1S/C20H24N10O14P2.2Na/c21-19-25-13-7(15(33)27-19)23-3-29(13)17-9(31)11-5(41-17)1-39-45(35,36)44-12-6(2-40-46(37,38)43-11)42-18(10(12)32)30-4-24-8-14(30)26-20(22)28-16(8)34;;/h3-6,9-12,17-18,31-32H,1-2H2,(H,35,36)(H,37,38)(H3,21,25,27,33)(H3,22,26,28,34);;/q;2*+1/p-2/t5-,6-,9-,10-,11-,12-,17-,18-;;/m1../s1 |
| SMILES | C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(NC4=O)N)O)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C6N=C(NC7=O)N)O)OP(=O)(O1)[O-])[O-].[Na+].[Na+] |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Defined linkage isomers and counterion forms allow controlled comparisons across cyclic-dinucleotide assay conditions.
Method limitations
- Activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
These points describe c-di-GMP Disodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for c-di-GMP Disodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CDN-0008 and CAS 2222132-40-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Cyclic Dinucleotides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
- Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
- Cyclic G(2',5')pA(3',5')p is the metazoan second messenger produced by cGAS
- STING is a direct innate immune sensor of cyclic di-GMP
- Cyclic di-AMP secreted by Listeria monocytogenes activates a host type I interferon response
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.