Cap Analogs
m7G(5')ppp(5')(2'-OMe,m6A)pG ammonium salt
Quick view. A GAG(m6A) trinucleotide cap analog in ammonium-salt form for in-vitro RNA-synthesis research. CAS 71340-22-2 and the listed composition refer to the inner-salt/free-acid identity; ammonium stoichiometry is variable. CAS 71340-22-2. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
m7G(5')ppp(5')(2'-OMe,m6A)pG ammonium salt is classified as cap analogs (Formula C33H45N15O24P4 (inner salt/free acid); molecular weight 1159.69 (inner salt/free acid)).
m7G(5')ppp(5')(2'-OMe,m6A)pG ammonium salt — Trinucleotide cap analog for in-vitro RNA-synthesis research.
For m7G(5')ppp(5')(2'-OMe,m6A)pG ammonium salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP GAG(m6A) m7G(5')ppp(5')(2'OMe,m6A)pG Ammonium Salt
- m7Gpppm6AmpG ammonium salt
- CAP GAG(m6A)
- GAG(m6A) ammonium salt
Useful catalog search terms
- CAS 71340-22-2
- m7Gpppm6AmpG
Physicochemical data
| Related CAS | 71340-22-2 (inner salt/free acid) |
|---|---|
| Counterion form | Ammonium salt (xNH4; stoichiometry unspecified) |
| Nucleotide shorthand | m7G(5')ppp(5')(2'-OMe,m6A)pG |
| First transcribed nucleotide | 2'-O-methyl-N6-methyladenosine |
| Covalent InChIKey | DIMGFCCAJKOSNT-RKTALREWSA-N |
| Covalent InChI | InChI=1S/C33H45N15O24P4/c1-36-23-14-24(38-7-37-23)46(8-39-14)31-22(63-3)21(70-73(55,56)64-4-11-17(49)19(51)29(67-11)47-9-40-15-25(47)41-32(34)43-27(15)53)13(69-31)6-66-75(59,60)72-76(61,62)71-74(57,58)65-5-12-18(50)20(52)30(68-12)48-10-45(2)16-26(48)42-33(35)44-28(16)54/h7-13,17-22,29-31,49-52H,4-6H2,1-3H3,(H10-,34,35,36,37,38,41,42,43,44,53,54,55,56,57,58,59,60,61,62)/t11-,12-,13-,17-,18-,19-,20-,21-,22-,29-,30-,31-/m1/s1 |
| Covalent SMILES | CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)([O-])OC[C@@H]4[C@H]([C@H]([C@@H](O4)[N+]5=CN(C6=C5N=C(NC6=O)N)C)O)O)OP(=O)(O)OC[C@@H]7[C@H]([C@H]([C@@H](O7)N8C=NC9=C8N=C(NC9=O)N)O)O)OC |
| Canonical covalent SMILES | CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)([O-])OC[C@@H]4[C@H]([C@H]([C@@H](O4)[N+]5=CN(C6=C5N=C(NC6=O)N)C)O)O)OP(=O)(O)OC[C@@H]7[C@H]([C@H]([C@@H](O7)N8C=NC9=C8N=C(NC9=O)N)O)O)OC |
| PubChem CID | 164886586 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe m7G(5')ppp(5')(2'-OMe,m6A)pG ammonium salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
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Frequently asked questions
Can the package size for m7G(5')ppp(5')(2'-OMe,m6A)pG ammonium salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0013 and CAS 71340-22-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Cap Analogs product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
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