Cap Analogs
CAP m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG Sodium Salt
Quick view. CAP m7G(LNA)(5')ppp(5')(2'OMe,m6A)pG Sodium Salt is an LNA-modified m7G cap analog with m6A/2'-OMe downstream features for mRNA cap optimization. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%.
Product profile
CAP m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG Sodium Salt is classified as rna cap analog or cap-related nucleotide.
CAP m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG Sodium Salt can support enzyme-substrate, in-vitro transcription, polymerase-screening or analytical-reference studies as appropriate to its phosphate state.
For CAP m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG Sodium Salt, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Useful catalog search terms
- RNA cap analog or cap-related nucleotide
- conformationally locked sugar
- Cap Analogs
Physicochemical data
| Key chemistry motifs | conformationally locked sugar |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical qualification includes identity, salt/counterion, assay basis, water content and enzyme compatibility.
- Related uses include LC-MS/HPLC method development and comparison with native or modified nucleotide controls.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe CAP m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
ARCA
Cap Analogs · CAS: 400806-46-4
BX-CA-0002CAP A(5')ppp(5')(2'-OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0003CAP 4 m7G(UNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
BX-CA-0004CAP 5 m7G(5')vppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: 3038327-80-6
BX-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: 2645354-92-1
BX-CA-0006CAP 7 m7G(HNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
Cap Analogs · CAS: N/A
Frequently asked questions
Can the package size for CAP m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CA-0026, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Cap Analogs product family and its named chemistry.