LNA Phosphoramidites
DMTr-2'-O-4'-C-Locked-rC(Ac)-3'-CE-Phosphoramidite
Quick view. A no-public-CAS N4-acetyl LNA cytidine 3'-CE phosphoramidite with formula C42H50N5O9P. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-4'-C-Locked-rC(Ac)-3'-CE-Phosphoramidite is classified as lna phosphoramidites (Formula C42H50N5O9P; molecular weight 799.86 g/mol).
DMTr-2'-O-4'-C-Locked-rC(Ac)-3'-CE-Phosphoramidite is useful for high-affinity probes, SNP/mismatch-discrimination studies, antisense designs and short sequence probes.
For DMTr-2'-O-4'-C-Locked-rC(Ac)-3'-CE-Phosphoramidite, high-affinity monomers require careful positional design; over-substitution may increase off-target binding or complicate synthesis.
Names and search terms
Confirmed or normalized name variants
- LNA-C(Ac)-CE Phosphoramidite
- 5'-O-DMTr-2'-O-4'-C-Locked-C(Ac) Phosphoramidite
Useful catalog search terms
- VLHUEAKCEPSXIL-WFNFTXKBSA-N
Physicochemical data
| InChIKey | VLHUEAKCEPSXIL-WFNFTXKBSA-N |
|---|---|
| CAS status | No public CAS assigned in the reviewed exact sources |
| Protected form | 5'-O-DMTr; N4-acetyl; 3'-CE phosphoramidite |
| InChI | InChI=1S/C42H50N5O9P/c1-28(2)47(29(3)4)57(54-25-11-23-43)56-38-37-39(46-24-22-36(44-30(5)48)45-40(46)49)55-41(38,26-52-37)27-53-42(31-12-9-8-10-13-31,32-14-18-34(50-6)19-15-32)33-16-20-35(51-7)21-17-33/h8-10,12-22,24,28-29,37-39H,11,25-27H2,1-7H3,(H,44,45,48,49)/t37-,38+,39-,41-,57?/m1/s1 |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@@H](O[C@]1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=CC(=NC6=O)NC(=O)C |
| Canonical SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H]2[C@@H](O[C@]1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=CC(=NC6=O)NC(=O)C |
| PubChem CID | 155293649 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Locked/bicyclic sugar motifs can substantially increase duplex thermal stability and mismatch discrimination.
Method limitations
- High-affinity monomers require careful positional design; over-substitution may increase off-target binding or complicate synthesis.
These points describe DMTr-2'-O-4'-C-Locked-rC(Ac)-3'-CE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
DMTr-2'-O-4'-C-Locked-5-Me-rC(Ac)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: N/A
BX-LP-0003DMTr-2'-O-4'-C-Locked-5-Me-rC(Bz)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 206055-82-5
BX-LP-0004DMTr-2'-O-4'-C-Locked-rA(Bz)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 206055-79-0
BX-LP-0005DMTr-2'-O-4'-C-Locked-rC(Bz)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: N/A
BX-LP-0006DMTr-2'-O-4'-C-Locked-rG(dmf)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 709641-79-2
BX-LP-0007DMTr-2'-O-4'-C-Locked-rG(iBu)-3'-CE-Phosphoramidite
LNA Phosphoramidites · CAS: 206055-77-8
Frequently asked questions
Can the package size for DMTr-2'-O-4'-C-Locked-rC(Ac)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-LP-0001, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
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