2'-O-MOE Phosphoramidites
DMTr-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite
Quick view. An N2-isobutyryl-protected 2'-O-MOE guanosine building block bearing a manufacturer-designated (L)-PSM phosphoramidite auxiliary for oligonucleotide synthesis research. A public CAS number is not assigned for this exact form. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite is classified as 2'-o-moe phosphoramidites (Formula C50H57N6O12PS; molecular weight 997.07).
DMTr-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite — N2-isobutyryl-protected 2'-O-MOE guanosine building block for PSM-based solid-phase oligonucleotide synthesis research.
For DMTr-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite
Useful catalog search terms
- C50H57N6O12PS
- N2-isobutyryl 2'-O-MOE guanosine PSM phosphoramidite
Physicochemical data
| CAS status | No public CAS assigned |
|---|---|
| 2'-O modification | 2-methoxyethyl (MOE) |
| Base protection | N2-isobutyryl |
| Phosphoramidite auxiliary | Manufacturer-designated (L)-PSM |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe DMTr-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
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BX-2OMP-0004DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite
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BX-2OMP-0006DMTr-2'-O-MOE-rA(Bz)-3'-(1-hydroxy-N,N-diisopropyl)phosphoramidite
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BX-2OMP-0007DMTr-2'-O-MOE-rA(DMTr)-3'-CE-Phosphoramidite
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Frequently asked questions
Can the package size for DMTr-2'-O-MOE-rG(iBu)-3'-(L)-PSM-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMP-0013, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-MOE Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.