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RNA (2'-O-TBDMS) Phosphoramidites

DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite

Quick view. DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite is an N4-acetyl- and 2'-O-TBDMS-protected cytidine building block for research-use RNA oligonucleotide synthesis. CAS 121058-88-6. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Constitutional structure of DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite
Chemical structure
Catalog numberBX-R2OT-0025
CAS number121058-88-6
Purity≥98%
Pack sizeCustom packaging by inquiry

Product profile

Material identity

DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite is classified as protected ribocytidine phosphoramidite (Formula C47H64N5O9PSi; molecular weight 902.10).

Typical application

DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite — N4-acetyl- and 2'-O-TBDMS-protected cytidine phosphoramidite building block for research-use RNA oligonucleotide synthesis.

Handling focus

For DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.

Names and search terms

Confirmed or normalized name variants

Useful catalog search terms

Physicochemical data

Base protectionN4-acetyl
Ribose protection2'-O-TBDMS
Synthesis format5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite
InChIInChI=1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m0/s1
InChIKeyQKWKXYVKGFKODW-ZYRNLWDWSA-N
SMILESCOc1ccc(C(OC[C@@H]2O[C@H](n3ccc(NC(C)=O)nc3=O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

Release documentation

Lot-specific CoA

The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.

Analytical package

Additional HPLC, MS or NMR documentation can be agreed during technical review where available.

Related products

Frequently asked questions

Can the package size for DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-Phosphoramidite be customized?

Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.

What information should be included in a quote request?

Quote catalog number BX-R2OT-0025 and CAS 121058-88-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.

Product-family literature

These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.

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Technology platforms

Catalog-derived platform membership for navigating related chemistry and verifiable product sets.