Modified Nucleosides
Xanthosine
Quick view. We supply Xanthosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 146-80-5. Catalog target purity: Specification on request.
Product profile
Xanthosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H12N4O6; molecular weight 284.23).
The deamination product of Guanosine. Potential biomarker for detecting radiation exposure. XANTHOSINE is used in the amplification of DNA isothermal strand displacement.
For Xanthosine, reported solubility: Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated). Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere.
Names and search terms
Confirmed or normalized name variants
- 9-[3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-3H-PURINE-2,6-DIONE
- 9-B-D-RIBOFURANOSYLXANTHINE
- 9-BETA-D-RIBOFURANOSYLXANTHINE
- XANTHINE-9-RIBOFURANOSIDE
- XANTHINE RIBOSIDE
- XANTHOSINE HYDRATE
- 1g
- Ribosylxanthin=Xao
Useful catalog search terms
- CAS 146-80-5
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | 1S/C10H12N4O6/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19)/t3-,5-,6-,9-/m1/s |
|---|---|
| InChIKey | UBORTCNDUKBEOP-UUOKFMHZSA-N |
| SMILES | O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(NC(N3)=O)=O)O[C@@H]1CO |
| Melting point | 174~176℃ |
| Density | 2.25±0.1 g/cm3(Predicted) |
| pKa | pK1:<2.5(+1);pK2:5.67(0);pK3:12.00(-1) (25°C) |
| Form | Solid |
| Color | White to Off-White |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Xanthosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for Xanthosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0784 and CAS 146-80-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.
