Sugars
2,3-Di-O-isopropylidene-D-ribonic-gama-lactone
Quick view. We supply 2,3-Di-O-isopropylidene-D-ribonic-gama-lactone as a protected or deoxygenated ribofuranose sugar building block for nucleoside and medicinal chemistry synthesis. CAS 30725-00-9. Catalog target purity: Specification on request.
Structure and identity
The structure drawing for this item is being finalized. Use the CAS number and machine-readable identifiers below to confirm the requested protecting groups, stereochemistry, salt or counterion and hydration state before ordering.
CAS, molecular formula, SMILES or InChI data are shown below when available.
We withhold a drawing when a related compound, alternate salt or incompletely specified stereoisomer could be mistaken for the requested material.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
2,3-Di-O-isopropylidene-D-ribonic-gama-lactone is classified as carbohydrate or ribofuranose building block (Formula C8H12O5; molecular weight 188.18).
2,3-Di-O-isopropylidene-D-ribonic-gama-lactone — 2,3-O-Isopropylidene-D-ribonic acid-1,4-lactone is used for the synthesis of C-nucleosides, prostanoids and GABA analogs via homochiral 2-piperidones. It is the starting material for the preparation of biochemical compounds including C-nucleosides, such as neplanocin A, and GABA analogs, via homochiral 2-piperidones.
For 2,3-Di-O-isopropylidene-D-ribonic-gama-lactone, reported solubility: Soluble in methanol at 50mg/ml, acetone, dichloromethane, ethyl Acetate. Storage: Keep in dark place,Sealed in dry,Room Temperature.
Names and search terms
Confirmed or normalized name variants
- 2,3-O-Isopropylidene-D-ribonic gamma-lactone
- 2,3-ISOPROPYLIDENE-D-RIBONO-1,4-LACTONE
- 2,3-ISOPROPYLIDENE-D-RIBONOLACTONE
- 2,3-O-ISOPROPYLIDENE-D-RIBONIC ACID GAMMA LACTONE
- 2,3-O-ISOPROPYLIDENE-D-RIBONO-1,4-LACTONE
- ISOPROPYLIDENE-D-RIBONOLACTONE
- 2,3-o-isopropylidene-d-ribonic γ-lactone
- D-Ribonic acid, 2,3-O-(1-methylethylidene)-,.gamma.-lactone
Useful catalog search terms
- CAS 30725-00-9
- Carbohydrate or ribofuranose building block
- Sugars
Physicochemical data
| Melting point | 135-139 °C |
|---|---|
| Boiling point | 243.17°C (rough estimate) |
| Density | 1.2069 (rough estimate) |
| pKa | 13.68±0.10(Predicted) |
| Form | Powder |
| Color | White to Off-white |
| SMILES | [C@H]12OC(C)(C)O[C@H]1C(O[C@@H]2CO)=O |&1:0,6,9,r| |
| InChI | InChI=1/C8H12O5/c1-8(2)12-5-4(3-9)11-7(10)6(5)13-8/h4-6,9H,3H2,1-2H3/t4-,5-,6-/s |
| InChIKey | NHHKFJCWLPPNCN-WKRIEWPCNA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 2,3-Di-O-isopropylidene-D-ribonic-gama-lactone can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
1,2-dideoxy ribofuranose
Sugars · CAS: 91547-59-0
BX-SUGA-00023-deoxy-1,2-O-isopropylidene-α-D-ribofuranose
Sugars · CAS: 3396-71-2
BX-SUGA-0011Lactose (Galβ1→4Glc)
Sugars · CAS: 63-42-3
BX-SUGA-0012Maltose monohydrate (Glcα1→4Glc)
Sugars · CAS: 6363-53-7
BX-SUGA-0013Isomaltose (Glcα1→6Glc)
Sugars · CAS: 499-40-1
BX-SUGA-0014Lactulose (Galβ1→4Fru)
Sugars · CAS: 4618-18-2
Frequently asked questions
Can the package size for 2,3-Di-O-isopropylidene-D-ribonic-gama-lactone be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-SUGA-0042 and CAS 30725-00-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.