Protected Nucleosides
3'-O-TBDMS-2'-dC(Bz)
Quick view. We supply 3'-O-TBDMS-2'-dC(Bz) as a silyl-protected ribonucleoside intermediate for RNA monomer and specialty nucleoside synthesis. CAS 51549-37-2. Catalog target purity: Specification on request.
Product profile
3'-O-TBDMS-2'-dC(Bz) is classified as nucleoside or protected nucleoside intermediate (Formula C22H31N3O5Si; molecular weight 445.58).
3'-O-TBDMS-2'-dC(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-O-TBDMS-2'-dC(Bz), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-TBDMS-N4-Bz-dC
- CYTIDINE, N-BENZOYL-2'-DEOXY-3'-O-[(1,1-DIMETHYLE...
- Cytidine, N-benzoyl-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-
- SCHEMBL9702839
Useful catalog search terms
- CAS 51549-37-2
- Nucleoside or protected nucleoside intermediate
- TBDMS protection
- Protected Nucleosides
Physicochemical data
| Key chemistry motifs | TBDMS protection |
|---|---|
| InChI | InChI=1S/C22H31N3O5Si/c1-22(2,3)31(4,5)30-16-13-19(29-17(16)14-26)25-12-11-18(24-21(25)28)23-20(27)15-9-7-6-8-10-15/h6-12,16-17,19,26H,13-14H2,1-5H3,(H,23,24,27,28)/t16-,17+,19+/m0/s |
| InChIKey | XZESDHQEKGJAIW-YQVWRLOYSA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O[C@@H]1CO)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 3'-O-TBDMS-2'-dC(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0111 and CAS 51549-37-2, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.