Protected Nucleosides
N2-Isobutyryl-3'-O-TBDMS-2'-deoxyguanosine
Quick view. A 2'-deoxyguanosine building block bearing N2-isobutyryl base protection, a 3'-O-TBDMS group, and a free 5'-hydroxyl group. CAS 99540-94-0. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.

Product profile
N2-Isobutyryl-3'-O-TBDMS-2'-deoxyguanosine is classified as protected nucleosides (Formula C20H33N5O5Si; molecular weight 451.60).
N2-Isobutyryl-3'-O-TBDMS-2'-deoxyguanosine — Identity-defined protected 2'-deoxyguanosine building block for research workflows involving nucleoside, nucleotide, and oligonucleotide chemistry.
For N2-Isobutyryl-3'-O-TBDMS-2'-deoxyguanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-TBDMS-2'-dG(iBu)
- 3'-O-TBDMS-N2-iBu-dG
- N2-Isobutyryl-3'-O-tert-butyldimethylsilyl-2'-deoxyguanosine
Useful catalog search terms
- CAS 99540-94-0
Physicochemical data
| Furanose stereochemistry | (2R,4S,5R) |
|---|---|
| Nucleoside | 2'-Deoxyguanosine |
| Base protection | N2-Isobutyryl |
| Sugar protection | 3'-O-TBDMS |
| Free hydroxyl group | 5' |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Frequently asked questions
Can the package size for N2-Isobutyryl-3'-O-TBDMS-2'-deoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0115 and CAS 99540-94-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.
