Protected Nucleosides
5'-O-(4,4'-Dimethoxy trityl)-3'-O-(2-methoxyethyl)-5-methyluridine
Quick view. We supply 5'-O-(4,4'-Dimethoxy trityl)-3'-O-(2-methoxyethyl)-5-methyluridine as a protected nucleoside intermediate for DNA/RNA analog synthesis and medicinal chemistry workflows. CAS 256223-94-6. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
5'-O-(4,4'-Dimethoxy trityl)-3'-O-(2-methoxyethyl)-5-methyluridine is classified as nucleoside or protected nucleoside intermediate.
5'-O-(4,4'-Dimethoxy trityl)-3'-O-(2-methoxyethyl)-5-methyluridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-(4,4'-Dimethoxy trityl)-3'-O-(2-methoxyethyl)-5-methyluridine, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Names and search terms
Useful catalog search terms
- CAS 256223-94-6
- Nucleoside or protected nucleoside intermediate
- 2'-O-MOE modification
- Protected Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-O-MOE modification |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-O-(4,4'-Dimethoxy trityl)-3'-O-(2-methoxyethyl)-5-methyluridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-O-(4,4'-Dimethoxy trityl)-3'-O-(2-methoxyethyl)-5-methyluridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0362 and CAS 256223-94-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.