Other Protected Nucleosides
2',3'-di-O-iBu-rG(iBu)
Quick view. We supply 2',3'-di-O-iBu-rG(iBu) as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 56489-75-9. Catalog target purity: ≥95%.

Product profile
2',3'-di-O-iBu-rG(iBu) is classified as nucleoside or protected nucleoside intermediate (Formula C22H31N5O8; molecular weight 493.51).
2',3'-di-O-iBu-rG(iBu) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2',3'-di-O-iBu-rG(iBu), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O, 3'-O, N2-triisobutyrylguanosine
- 5’-HO-tri(iBu)G, N2-Isobutyroyl-2’,3’-di-O-isobutyroyl guanosine
- Guanosine, N-(2-methyl-1-oxopropyl)-, 2',3'-bis(2-methylpropanoate)
Useful catalog search terms
- CAS 56489-75-9
- Nucleoside or protected nucleoside intermediate
- Other Protected Nucleosides
Physicochemical data
| SMILES | O([C@@H]1[C@@H]([C@@H](CO)O[C@H]1N1C=NC2C(NC(NC(=O)C(C)C)=NC1=2)=O)OC(=O)C(C)C)C(=O)C(C)C |&1:1,2,3,7,r| |
|---|---|
| InChIKey | JJRMTPVXETZPOA-RDELIJMJNA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Related products
Frequently asked questions
Can the package size for 2',3'-di-O-iBu-rG(iBu) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0001 and CAS 56489-75-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Other Protected Nucleosides product family and its named chemistry.
