Modified Nucleosides
2', 3'-Dideoxyguanosine
Quick view. We supply 2', 3'-Dideoxyguanosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 85326-06-3. Catalog target purity: Specification on request.
Product profile
2', 3'-Dideoxyguanosine is classified as nucleoside or protected nucleoside intermediate (Formula C10H13N5O3; molecular weight 251.24).
2', 3'-Dideoxyguanosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2', 3'-Dideoxyguanosine, storage: 2-8°C. Form: Powder.
Names and search terms
Confirmed or normalized name variants
- BETA-D-2',3'-DIDEOXYGUANOSINE
- DDG
- 2',3'-Didioxyguanosine
- 2',3'-Dideoxy-D-guanosine
- 2-Amino-9-[5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
- ddGuo
Useful catalog search terms
- CAS 85326-06-3
- Nucleoside or protected nucleoside intermediate
- Modified Nucleosides
Physicochemical data
| InChI | InChI=1S/C10H13N5O3/c11-10-13-8-7(9(17)14-10)12-4-15(8)6-2-1-5(3-16)18-6/h4-6,16H,1-3H2,(H3,11,13,14,17)/t5-,6+/m0/s |
|---|---|
| InChIKey | OCLZPNCLRLDXJC-UHFFFAOYSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)CC1 |
| Density | 1.91±0.1 g/cm3(Predicted) |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2', 3'-Dideoxyguanosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2', 3'-Dideoxyguanosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0697 and CAS 85326-06-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry.