Amino-modified Nucleosides
2'-Amino-2'-deoxycytidine
Quick view. We supply 2'-Amino-2'-deoxycytidine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 26889-42-9. Catalog target purity: Specification on request.
Product profile
2'-Amino-2'-deoxycytidine is classified as nucleoside or protected nucleoside intermediate (Formula C9H14N4O4; molecular weight 242.23).
2'-Amino-2'-deoxycytidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-Amino-2'-deoxycytidine, storage: 2-8°C.
Names and search terms
Confirmed or normalized name variants
- 2'-NH2-dC
- 2'-NH2-2'-dC
- 2'-AMINO-D-CYTIDINE
- Cytidine, 2'-amino-2'-deoxy-
- 2'-Amino-2'-deoxy-D-cytidine
- Used for hammerhead ribozyme
- 2'-AMINO-D-CYTIDINE USP/EP/BP
- Cytidine,2'-amino-2'-deoxy- (8CI,9CI)
Useful catalog search terms
- CAS 26889-42-9
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C9H14N4O4/c10-5-1-2-13(9(16)12-5)8-6(11)7(15)4(3-14)17-8/h1-2,4,6-8,14-15H,3,11H2,(H2,10,12,16)/t4-,6-,7-,8-/m1/s |
| InChIKey | FECRKKQKJNKYNF-XVFCMESISA-N |
| SMILES | C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)N |
| Boiling point | 531.3±60.0 °C(Predicted) |
| Density | 1.89±0.1 g/cm3(Predicted) |
| pKa | 13.66±0.70(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2'-Amino-2'-deoxycytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-Amino-2'-deoxycytidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0066 and CAS 26889-42-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.