Amino-modified Nucleosides
2-(Cyclo hexyl methylidene hydrazino) adenosine
Quick view. We supply 2-(Cyclo hexyl methylidene hydrazino) adenosine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 144348-08-3. Catalog target purity: Specification on request.
Product profile
2-(Cyclo hexyl methylidene hydrazino) adenosine is classified as nucleoside or protected nucleoside intermediate (Formula C17H25N7O4; molecular weight 391.42).
2-(Cyclo hexyl methylidene hydrazino) adenosine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2-(Cyclo hexyl methylidene hydrazino) adenosine, reported solubility: DMSO: 125 mg/mL (319.35 mM; Need ultrasonic). Storage: Store at -20°C.
Names and search terms
Confirmed or normalized name variants
- binodenoson
- SHA 174
- SHA 211
- WRC 0470
- MRE 0470
- Binodisine
- 2-(cyclohexylmethylidenehydrazino)adenos
- 2-(Cyclhexyl methylidene hydrazino) adenosine
Useful catalog search terms
- CAS 144348-08-3
- Nucleoside or protected nucleoside intermediate
- amine functionality
- Amino-modified Nucleosides
Physicochemical data
| Key chemistry motifs | amine functionality |
|---|---|
| InChI | InChI=1S/C17H25N7O4/c18-14-11-15(22-17(21-14)23-20-6-9-4-2-1-3-5-9)24(8-19-11)16-13(27)12(26)10(7-25)28-16/h6,8-10,12-13,16,25-27H,1-5,7H2,(H3,18,21,22,23)/b20-6+/t10-,12-,13-,16-/m1/s |
| InChIKey | XJFMHMFFBSOEPR-XNIJJKJLSA-N |
| SMILES | OC[C@H]1O[C@@H](N2C3C(=C(N=C(NN=CC4CCCCC4)N=3)N)N=C2)[C@H](O)[C@@H]1O |
| Melting point | 154-157° |
| Boiling point | 765.6±70.0 °C(Predicted) |
| Density | 1.76 |
| pKa | 6.92±0.70(Predicted) |
| Form | Solid |
| Color | White to off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2-(Cyclo hexyl methylidene hydrazino) adenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2-(Cyclo hexyl methylidene hydrazino) adenosine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-AMN-0144 and CAS 144348-08-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry.