2'-F Nucleosides
2'-fluoro-2, 6-diaminopurine-2'-deoxyriboside
Quick view. We supply 2'-fluoro-2, 6-diaminopurine-2'-deoxyriboside as a 2'-fluoro nucleoside for modified nucleotide, amidite and nucleoside analog synthesis. CAS 134444-47-6. Catalog target purity: Specification on request.
Product profile
2'-fluoro-2, 6-diaminopurine-2'-deoxyriboside is classified as nucleoside or protected nucleoside intermediate (Formula C10H13FN6O3; molecular weight 284.25).
2'-fluoro-2, 6-diaminopurine-2'-deoxyriboside can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 2'-fluoro-2, 6-diaminopurine-2'-deoxyriboside, storage: under inert gas (nitrogen or Argon) at 2–8 °C. Form: Powder.
Names and search terms
Confirmed or normalized name variants
- 2-Amino-2'-deoxy-2'-fluoroadenosine
- 2-Amino-2'-F-2'-deoxy-adenosine
- 2-AMino-2'-fluoro-2'-deoxyadenosine
- 2-Amino-2'-deoxy-2'-fluoro-D-adenosine
- Adenosine, 2-aMino-2'-deoxy-2'-fluoro-
- Adenosine,2-amino-2'-deoxy-2'-fluoro- (9CI)
- 2-Amino-2'-deoxy-2'-fluoro-D-adenosine USP/EP/BP
- 2,6-Diamino-9-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-9H-purine
Useful catalog search terms
- CAS 134444-47-6
- Nucleoside or protected nucleoside intermediate
- 2'-fluoro modification
- amine functionality
- 2'-F Nucleosides
Physicochemical data
| Key chemistry motifs | 2'-fluoro modification; amine functionality |
|---|---|
| InChI | InChI=1S/C10H13FN6O3/c11-4-6(19)3(1-18)20-9(4)17-2-14-5-7(12)15-10(13)16-8(5)17/h2-4,6,9,18-19H,1H2,(H4,12,13,15,16)/t3-,4-,6-,9-/m1/s |
| InChIKey | MHWHYOFBOWTAHZ-DXTOWSMRSA-N |
| SMILES | C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N)N |
| Form | Powder |
| Color | White to Off-white |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-fluoro-2, 6-diaminopurine-2'-deoxyriboside or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-fluoro-2, 6-diaminopurine-2'-deoxyriboside be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FN-0234 and CAS 134444-47-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the 2'-F Nucleosides product family and its named chemistry.