Modified Nucleotides
2'-OMe-UTP Sodium Salt
Quick view. A sodium salt of uridine 5'-triphosphate bearing a 2'-O-methyl substituent and an unprotected 3'-hydroxyl group. The listed CAS refers to the free-acid identity. CAS 143028-99-3. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
2'-OMe-UTP Sodium Salt is classified as modified nucleotides.
2'-OMe-UTP Sodium Salt supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For 2'-OMe-UTP Sodium Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Methyl-UTP Sodium Salt
- 2'-O-Methyluridine 5'-triphosphate Sodium Salt
- 2'OMe-UTP Na
- 2'-Methoxy-UTP Sodium Salt
Useful catalog search terms
- 143028-99-3
Physicochemical data
| Free-acid molecular formula | C10H17N2O15P3 |
|---|---|
| Free-acid molecular weight | 498.17 |
| CAS basis | Free-acid identity |
| Salt form | Sodium salt |
| Counterion stoichiometry | Not specified |
| Sugar modification | 2'-O-methyl |
| Hydroxyl state | 3' hydroxyl unprotected |
| Phosphate state | 5'-triphosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-OMe-UTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 2'-OMe-UTP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0036 and CAS 143028-99-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.