Protected Nucleosides
3',5'-di-O-acetylthymidine
Quick view. We supply 3',5'-di-O-acetylthymidine as a base- or sugar-protected nucleoside intermediate for nucleoside, nucleotide and oligonucleotide building-block synthesis. CAS 6979-97-1. Catalog target purity: Specification on request.
Product profile
3',5'-di-O-acetylthymidine is classified as nucleoside or protected nucleoside intermediate (Formula C14H18N2O7; molecular weight 326.3).
3',5'-di-O-acetylthymidine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3',5'-di-O-acetylthymidine, storage: 0-6°C.
Names and search terms
Confirmed or normalized name variants
- 1-(3,5-Di-O-acetyl-2-deoxypentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
- DIACETYL THYMIDINE
- 3',5'-DIACETYLTHYMIDINE
- Thymidine, 3',5'-diacetate
- 3'-O,5'-O-Diacetylthymidine
- 1'(2'-DEOXY-3',5'-DI-O-ACETYL-BETA-D-RIBOFURANOSYL)THYMINE
- 1-(3-O,5-O-Diacetyl-2-deoxy-β-D-ribofuranosyl)-5-methyl-1,2,3,4-tetr
Useful catalog search terms
- CAS 6979-97-1
- Nucleoside or protected nucleoside intermediate
- Protected Nucleosides
Physicochemical data
| InChI | InChI=1S/C14H18N2O7/c1-7-5-16(14(20)15-13(7)19)12-4-10(22-9(3)18)11(23-12)6-21-8(2)17/h5,10-12H,4,6H2,1-3H3,(H,15,19,20) |
|---|---|
| InChIKey | RGVBNBFNSBMXID-UHFFFAOYSA-N |
| SMILES | CC(=O)OCC1OC(n2cc(C)c(O)nc2=O)CC1OC(C)=O |
| Melting point | 126-128 °C(lit.) |
| Boiling point | 463.51°C (rough estimate) |
| Density | 1.2368 (rough estimate) |
| pKa | 9.55±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 3',5'-di-O-acetylthymidine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0268 and CAS 6979-97-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.