dNTPs
3′-O-Azidomethyl-dATP Sodium Salt
Quick view. We supply 3′-O-Azidomethyl-dATP Sodium Salt as a 3'-O-azidomethyl reversible-terminator dNTP for controlled DNA polymerase extension and sequencing-chemistry development. CAS 1048021-78-8. Catalog target purity: Specification on request.
Product profile
3′-O-Azidomethyl-dATP Sodium Salt is classified as specialty research-use chemical building block (Formula C11H17N8O12P3; molecular weight 546.22).
3′-O-Azidomethyl-dATP Sodium Salt — 3′-O-N3-dATP (3′-O-Azidomethyl dATP) is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm-1, which determines the DNA sequences continuously.
For 3′-O-Azidomethyl-dATP Sodium Salt, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- 3'-azidomethyl-dATP
- 3'-azidomethyl-2'-Deoxyadenosine-5'-Triphosphate
- adenosine 5'-(tetrahydrogen triphosphate), 2'-deoxy-3'-O-(azidomethyl)-
Useful catalog search terms
- CAS 1048021-78-8
- Specialty research-use chemical building block
- azide click handle
- dNTPs
Physicochemical data
| Key chemistry motifs | azide click handle |
|---|---|
| CAS context | The listed CAS refers to the parent/free-acid identity; confirm the supplied salt or counterion in the current specification. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- 3′-O-Azidomethyl-dATP Sodium Salt can be used as a defined research input for chemistry feasibility, analytical method development and material comparison.
- Typical qualification includes identity, purity method, storage, handling and downstream workflow compatibility.
- Related analogs, impurity standards and custom quantities can be reviewed for project-specific research needs.
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
These points describe 3′-O-Azidomethyl-dATP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 3′-O-Azidomethyl-dATP Sodium Salt be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-DNTP-0038 and CAS 1048021-78-8, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 3′-O-Azidomethyl-dATP Sodium Salt or the named structural feature represented by this product.