Protected Nucleosides
3'-O-TBDMS-2'-dA(Bz)
Quick view. We supply 3'-O-TBDMS-2'-dA(Bz) as a silyl-protected ribonucleoside intermediate for RNA monomer and specialty nucleoside synthesis. CAS 51549-40-7. Catalog target purity: Specification on request.
Product profile
3'-O-TBDMS-2'-dA(Bz) is classified as nucleoside or protected nucleoside intermediate (Formula C23H31N5O4Si; molecular weight 469.61).
3'-O-TBDMS-2'-dA(Bz) can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-O-TBDMS-2'-dA(Bz), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-TBDMS-N6-Bz-dA
- Adenosine, N-benzoyl-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimet...
- N-Benzoyl-2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-Adenosine
- Adenosine,N-benzoyl-2'-deoxy-3'-o-[(1,1-dimethylethyl)dimethylsilyl]-
- SCHEMBL9703679
Useful catalog search terms
- CAS 51549-40-7
- Nucleoside or protected nucleoside intermediate
- TBDMS protection
- Protected Nucleosides
Physicochemical data
| Key chemistry motifs | TBDMS protection |
|---|---|
| Density | 1.28±0.1 g/cm3(Predicted) |
| pKa | 7.87±0.43(Predicted) |
| InChI | InChI=1S/C23H31N5O4Si/c1-23(2,3)33(4,5)32-16-11-18(31-17(16)12-29)28-14-26-19-20(24-13-25-21(19)28)27-22(30)15-9-7-6-8-10-15/h6-10,13-14,16-18,29H,11-12H2,1-5H3,(H,24,25,27,30)/t16-,17+,18+/m0/s |
| InChIKey | JGELYOCTJSVMRL-RCCFBDPRSA-N |
| SMILES | CC(C)(C)[Si](C)(C)O[C@H]1C[C@@H](O[C@@H]1CO)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
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Frequently asked questions
Can the package size for 3'-O-TBDMS-2'-dA(Bz) be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0114 and CAS 51549-40-7, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry.