3'-O-Me Nucleosides
3'-OMe-pseudouridine
Quick view. We supply 3'-OMe-pseudouridine as a 3'-O-methyl nucleoside for cap analog, modified RNA and protected nucleoside chemistry. CAS 51293-40-4. Catalog target purity: Specification on request.
Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Product profile
3'-OMe-pseudouridine is classified as nucleoside or protected nucleoside intermediate.
3'-OMe-pseudouridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 3'-OMe-pseudouridine, modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
Names and search terms
Useful catalog search terms
- CAS 51293-40-4
- Nucleoside or protected nucleoside intermediate
- 3'-O-Me Nucleosides
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Base modifications can tune RNA stability, translation behavior, duplex properties or analytical discrimination versus native bases.
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- Modification benefits are context-dependent; transcript length, substitution level, enzyme system and analytical purity can change the observed outcome.
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-OMe-pseudouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-O-Me-rA
3'-O-Me Nucleosides · CAS: 10300-22-8
BX-MN-01573'-O-Me-rG
3'-O-Me Nucleosides · CAS: 10300-27-3
BX-3OMN-00023'-O-Methyl-2'-O-acetyl-5'-O-benzoyluridine
3'-O-Me Nucleosides · CAS: 2072145-71-0
BX-3OMN-00033'-O-Methyl-4-deoxyuridine
3'-O-Me Nucleosides · CAS: 2095417-12-0
BX-3OMN-00043'-OMe-N1-Me-pseudouridine
3'-O-Me Nucleosides · CAS: 2254248-90-1
BX-3OMN-00053'-O-Methyl-5-methyluridine
3'-O-Me Nucleosides · CAS: 2305415-87-4
Frequently asked questions
Can the package size for 3'-OMe-pseudouridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-3OMN-0007 and CAS 51293-40-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 3'-OMe-pseudouridine or the named structural feature represented by this product.