Modified Nucleosides
5-(2-Hyroxyethyl)-2'-deoxyuridine
Quick view. We supply 5-(2-Hyroxyethyl)-2'-deoxyuridine as a specialty product for nucleic acid chemistry and oligonucleotide research workflows. CAS 90301-60-3. Catalog target purity: Specification on request.
Product profile
5-(2-Hyroxyethyl)-2'-deoxyuridine is classified as nucleoside or protected nucleoside intermediate (Formula C11H16N2O6; molecular weight 272.25).
5-(2-Hyroxyethyl)-2'-deoxyuridine can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5-(2-Hyroxyethyl)-2'-deoxyuridine, dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
Names and search terms
Confirmed or normalized name variants
- 5-(2-Hydroxy-ethyl)-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
- 5-Hydroxyethyl-2'-Deoxyuridine
- 2'-Deoxy-5-(2-hydroxyethyl)uridine
- 5-(2-HYDROXYETHYL)-2'-DEOXYURIDINE
- Uridine, 2'-deoxy-5-(2-hydroxyethyl)-
Useful catalog search terms
- CAS 90301-60-3
- Nucleoside or protected nucleoside intermediate
- fluorescent label
- Modified Nucleosides
Physicochemical data
| Key chemistry motifs | fluorescent label |
|---|---|
| InChI | InChI=1S/C11H16N2O6/c14-2-1-6-4-13(11(18)12-10(6)17)9-3-7(16)8(5-15)19-9/h4,7-9,14-16H,1-3,5H2,(H,12,17,18)/t7-,8+,9+/m0/s |
| InChIKey | SORQWSCHVYGEPE-DJLDLDEBSA-N |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)CCO)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Fluorescent labels enable non-radioactive detection and can reduce downstream staining or secondary-label steps.
Method limitations
- Dye-labeled nucleotides or amidites are bulkier than native monomers; incorporation efficiency, label density, photobleaching and light exposure should be controlled.
These points describe 5-(2-Hyroxyethyl)-2'-deoxyuridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-(2-Hyroxyethyl)-2'-deoxyuridine be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-MN-0709 and CAS 90301-60-3, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss 5-(2-Hyroxyethyl)-2'-deoxyuridine or the named structural feature represented by this product.