DMTr-protected Nucleosides
5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU
Quick view. We supply 5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU as a DMTr-protected nucleoside intermediate for selective oligonucleotide building-block synthesis. CAS 242147-79-1. Catalog target purity: ≥95%.
Product profile
5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU is classified as nucleoside or protected nucleoside intermediate (Formula C33H37N3O8; molecular weight 603.66).
5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU can serve as a starting material, protected intermediate or analytical comparator in nucleoside and nucleotide route development.
For 5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 2’-O-(2-aminoethyl)-5’-O-DMTr-5-methyluridine
- 2'-O-(2-aminoethyl)-5'-O-(4,4'-dimethoxytrityl)-5-methyluridine
- Uridine, 2'-O-(2-aminoethyl)-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-
- 5'-O-DMT-2'-O-(2-aminoethyl) -5-Me-rU
Useful catalog search terms
- CAS 242147-79-1
- Nucleoside or protected nucleoside intermediate
- DMTr/DMT protection
- amine functionality
- DMTr-protected Nucleosides
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; amine functionality |
|---|---|
| Density | 1.34±0.1 g/cm3(Predicted) |
| pKa | 9.55±0.10(Predicted) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
- We release this product against the stated purity specification; the lot-specific CoA provides the result and analytical basis.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical work includes protection/deprotection studies, phosphorylation or phosphitylation route scouting and impurity identification.
- The material can support medicinal-chemistry analog preparation and process-development feasibility studies.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5'-O-DMTr-2'-O-(2-aminoethyl) -5-Me-rU be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-PN-0027 and CAS 242147-79-1, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry.