dNTPs
5-Propargylamino-dUTP
Quick view. A C5-propargylamino-modified dUTP for modified-nucleotide incorporation and DNA-labeling research. CAS 179101-49-6. Catalog target purity: >98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
5-Propargylamino-dUTP is classified as dntps (Formula C12H18N3O14P3 (free-acid basis); molecular weight 521.20 (free-acid basis)).
5-Propargylamino-dUTP — Modified dUTP incorporation in enzymatic DNA synthesis research
For 5-Propargylamino-dUTP, copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
Names and search terms
Confirmed or normalized name variants
- 5-PA-dUTP
- Aminopropargyl-dUTP
- 5-Propargylamino-2'-deoxyuridine 5'-triphosphate
Useful catalog search terms
- 179101-49-6
Physicochemical data
| Modification | C5 propargylamino group on dUTP |
|---|---|
| Supply Form | Sodium-salt aqueous solution, triethylamine solution, or powder; confirm requested form |
| Solution Appearance | Colorless to slightly yellow |
| Powder Appearance | White to off-white |
| Solution concentration | 100-110 mM; pH 7.5 +/-0.5 |
| Storage temperature | Solution: -20 C; powder: 2-8 C, dark and dry |
| UV Maximum | 289 nm |
| PubChem CID | 18664765 |
| InChIKey | BGGIMXKBIBMKBL-IVZWLZJFSA-N |
| InChI | InChI=1S/C12H18N3O14P3/c13-3-1-2-7-5-15(12(18)14-11(7)17)10-4-8(16)9(27-10)6-26-31(22,23)29-32(24,25)28-30(19,20)21/h5,8-10,16H,3-4,6,13H2,(H,22,23)(H,24,25)(H,14,17,18)(H2,19,20,21)/t8-,9+,10+/m0/s1 |
| SMILES | NCC#Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- DNA labeling and downstream conjugation through the propargylamino handle
Product-specific evaluation notes
Potential advantages
- Click-compatible handles separate oligonucleotide synthesis from late-stage labeling, which helps screen multiple payloads from a common intermediate.
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Copper-catalyzed, copper-free or inverse-electron-demand click conditions can affect sensitive oligonucleotides differently; residual metal, solvent and purification strategy should be controlled.
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 5-Propargylamino-dUTP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for 5-Propargylamino-dUTP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GSS-0009 and CAS 179101-49-6, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact BX Lab product, supplied form, lot specification, availability or performance.
Technology platforms
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