Cyclic Dinucleotides
c-di-GMP
Quick view. Cyclic bis(3',5')-diguanylate for bacterial second-messenger and STING ligand-response research; formula and molecular weight are stated on a free-acid basis. CAS 61093-23-0. Catalog target purity: >99% HPLC. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
c-di-GMP is classified as cyclic dinucleotides (Formula C20H24N10O14P2 (free-acid basis); molecular weight 690.41 (free-acid basis)).
c-di-GMP — Bacterial cyclic-dinucleotide and second-messenger research
For c-di-GMP, activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
Names and search terms
Confirmed or normalized name variants
- Cyclic di-GMP
- cyclic diguanosine monophosphate
- cyclic diguanylate
Useful catalog search terms
- 61093-23-0
Physicochemical data
| PubChem ID | 135440063 |
|---|---|
| Linkage | Cyclic bis(3',5')-diguanylate |
| Parent InChIKey | PKFDLKSEZWEFGL-MHARETSRSA-N |
| Supply Form | Sodium-salt products are common; confirm counterion stoichiometry for the requested material |
| Physical form | White to off-white solid |
| Storage temperature | -20 C |
| InChI | InChI=1S/C20H24N10O14P2/c21-19-25-13-7(15(33)27-19)23-3-29(13)17-9(31)11-5(41-17)1-39-45(35,36)44-12-6(2-40-46(37,38)43-11)42-18(10(12)32)30-4-24-8-14(30)26-20(22)28-16(8)34/h3-6,9-12,17-18,31-32H,1-2H2,(H,35,36)(H,37,38)(H3,21,25,27,33)(H3,22,26,28,34)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1 |
| InChIKey | PKFDLKSEZWEFGL-MHARETSRSA-N |
| SMILES | C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3NC(=NC4=O)N)O)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C6NC(=NC7=O)N)O)OP(=O)(O1)O)O |
| ChEBI ID | CHEBI:49537 |
| Net charge | 0 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- STING ligand-response and binding studies
Product-specific evaluation notes
Potential advantages
- Defined linkage isomers and counterion forms allow controlled comparisons across cyclic-dinucleotide assay conditions.
Method limitations
- Activity can depend on linkage stereochemistry, receptor variant, cell entry, salt form and assay format; molar calculations should use the exact supplied form.
These points describe c-di-GMP or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for c-di-GMP be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-CDN-0014 and CAS 61093-23-0, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not a BX Lab lot specification or product-performance claim.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.