2'-Fluoro Phosphoramidites
DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite
Quick view. DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite is an L-DPSE-configured 2'-fluoro N2-isobutyryl guanosine building block for research-use stereodefined oligonucleotide synthesis. CAS 2227139-97-9. Catalog target purity: ≥95%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite is classified as l-dpse 2'-fluoro guanosine phosphoramidite (Formula C54H58FN6O8PSi; molecular weight 997.10).
DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite — L-DPSE-configured 2'-fluoro N2-isobutyryl guanosine phosphoramidite building block for research-use stereodefined oligonucleotide synthesis.
For DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite
- N2-Isobutyryl-5'-O-DMTr-2'-fluoro-dG-3'-(L)-DPSE-Phosphoramidite
Useful catalog search terms
- 2227139-97-9
- PubChem 178421319
- C54H58FN6O8PSi
- Synthgene PA247
Physicochemical data
| Base protection | N2-isobutyryl |
|---|---|
| Sugar modification | 2'-fluoro |
| Phosphorus auxiliary | L-DPSE |
| InChIKey | GSSYTHNLCHZVRD-ABIOHNQMSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
DMTr-(2'R)-2'-F-2'-Me-dU-3'-CE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0002DMTr-2'-F-dA(Bz)-3'-(D)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 1528734-00-0
BX-2FP-0003DMTr-2'-F-dC(Bz)-3'-(D)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0004DMTr-2'-F-dC(Bz)-3'-(L)-DPSE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0005DMTr-2'-F-dG(dmf)-3'-(L)-PSM-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: N/A
BX-2FP-0006DMTr-2'-F-dG(dmf)-3'-CE-Phosphoramidite
2'-Fluoro Phosphoramidites · CAS: 3081868-42-7
Frequently asked questions
Can the package size for DMTr-2'-F-dG(iBu)-3'-(L)-DPSE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2FP-0022 and CAS 2227139-97-9, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-Fluoro Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.