2'-O-Me Phosphoramidites
DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite
Quick view. DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite is an N6-benzoyl-protected 2'-O-methyl adenosine building block bearing an L-DPSE phosphoramidite auxiliary for research-use oligonucleotide synthesis. CAS 1528733-90-5. Catalog target purity: ≥98%. Availability: Inquiry only — contact BX Lab to confirm current availability.
Product profile
DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite is classified as protected 2'-o-methyl riboadenosine phosphoramidite (Formula C58H59N6O8PSi; molecular weight 1027.20).
DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite — N6-benzoyl-protected 2'-O-methyl adenosine building block bearing an L-DPSE phosphoramidite auxiliary for research-use oligonucleotide synthesis.
For DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- DMT-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite
Useful catalog search terms
- 1528733-90-5
- PubChem 178421405
- C58H59N6O8PSi
- Synthgene PA238
- BOC Sciences BRP-02804
- 2'-O-Me Phosphoramidites
Physicochemical data
| Base protection | N6-benzoyl |
|---|---|
| Ribose modification | 2'-O-methyl |
| 5' protection | DMTr |
| Phosphorus auxiliary | L-DPSE |
| InChIKey | YPNIDBLCASOAIX-NEQFEEGOSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for DMTr-2'-O-Me-rA(Bz)-3'-(L)-DPSE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-2OMP-0066 and CAS 1528733-90-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
These publications provide peer-reviewed context for the 2'-O-Me Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.