RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite
Quick view. We supply DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite as a standard adenosine monomer for RNA solid-phase synthesis. CAS 104992-55-4. Catalog target purity: Specification on request.
Product profile
DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C53H66N7O8PSi; molecular weight 988.19).
DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite, reported solubility: DMSO: Sparingly soluble: 1-10 mg/ml Ethanol: Sparingly soluble: 1-10 mg/ml. Storage: Inert atmosphere,Store in freezer, under -20°C.
Names and search terms
Confirmed or normalized name variants
- 2'-TBDMS-A CEP
- N-Benzoyl-5-O-(4
- 8-Aza-7-deaza-A CEP
- Bz-rA Phosphoramidite
- N-diisopropyl)phosphoramidite
- 2’-TBDMS-rA(N-Bz) Phosphoramidite
- 2'-TBDMS -Bz-rA-CE-Phosphoramidite
- 5'-O-DMT-2'-TBDMS-rA(N-Bz)-3'-CEDPA
Useful catalog search terms
- CAS 104992-55-4
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- TBDMS protection
- phosphoramidite coupling group
- 2'-O-TBDMS-rA(Bz) Phosphoramidite
- BX-R2OT-0010
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; TBDMS protection; phosphoramidite coupling group |
|---|---|
| Form | powder |
| Color | white to off-white |
| SMILES | COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7 |
| InChIKey | FFXHNCNNHASXCT-RFMFGJHUSA-N |
| InChI | InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
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Frequently asked questions
Can the package size for DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-R2OT-0023 and CAS 104992-55-4, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry.