RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite
Quick view. We supply DMTr-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite as a dmf-protected guanosine RNA amidite for standard TBDMS RNA synthesis. CAS 149559-87-5. Catalog target purity: ≥98%.
Product profile
DMTr-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block (Formula C49H67N8O8PSi; molecular weight 955.18).
DMTr-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- RNA "G" phosphoramidite
- DMT-2'-O-TBDMS-G(dmf)-CE-Phosphoramidite
- 5'-O-DMT-2'-O-TBDMS-N2-DMF-Guanosine 3'-CE phosphoramidite
- DMT-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite
- DMTr-2'-O-TBDMS-rG(dmf)-3'-2-cyanoethyl phosphoramidite
- 2'-O-TBDMS-rG(dmf) Phosphoramidite
- BX-R2OT-0015
Useful catalog search terms
- CAS 149559-87-5
- Protected oligonucleotide phosphoramidite building block
- DMTr/DMT protection
- TBDMS protection
- phosphoramidite coupling group
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Key chemistry motifs | DMTr/DMT protection; TBDMS protection; phosphoramidite coupling group |
|---|
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(((E)-(dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
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Frequently asked questions
Can the package size for DMTr-2'-O-TBDMS-rG(dmf)-3'-CE-Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-R2OT-0009 and CAS 149559-87-5, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-family literature
The publications below provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry.