GalNAc
GalNAc PEG Cluster Phosphoramidite
Quick view. We supply GalNAc PEG Cluster Phosphoramidite as a PEG-spaced GalNAc cluster amidite for solid-phase synthesis of liver-targeted oligonucleotide conjugates. A public CAS number is not assigned for this exact form. Catalog target purity: ≥97%.
Product profile
GalNAc PEG Cluster Phosphoramidite is classified as protected oligonucleotide phosphoramidite building block.
GalNAc PEG Cluster Phosphoramidite can be evaluated as a monomer or functional building block in solid-phase oligonucleotide synthesis.
For GalNAc PEG Cluster Phosphoramidite, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Useful catalog search terms
- Protected oligonucleotide phosphoramidite building block
- GalNAc ligand motif
- phosphoramidite coupling group
- GalNAc
Physicochemical data
| Key chemistry motifs | GalNAc ligand motif; phosphoramidite coupling group |
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Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Typical development work includes coupling-condition screening, deprotection compatibility checks and LC-MS/HPLC characterization of test sequences.
- The material can also support related-analog comparison, impurity-reference preparation and route-development studies.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe GalNAc PEG Cluster Phosphoramidite or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Frequently asked questions
Can the package size for GalNAc PEG Cluster Phosphoramidite be customized?
Yes. Share the initial quantity, expected future scale, delivery timeline and packaging preference for review.
What information should be included in a quote request?
Quote catalog number BX-GALN-0004, the intended research workflow, required quantity and any additional HPLC, MS or NMR documentation needed.
Product-relevant literature
The publications below discuss GalNAc PEG Cluster Phosphoramidite or the named structural feature represented by this product.